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Table 2 Urinary Levels of Selected Antimicrobials |
|
Drug |
Dose* |
Urine concetration (µg/ml) |
Percent excreted in urine |
|
Amoxicillin Ampicillin Cephalexin Cinoxacin Ciprofloxacin Enoxacin Levofloxacin Methenamine Nalidixic Acid Nitrofurantoin Norfloxacin Ofloxacin Trimethoprim Trimethoprim-sulfamethoxazole |
250 mg 250 mg 250 mg 500 mg 500 mg dna 500 mg 1 gm 4 gm/24 hours 50-100 mg 400 mg 200 mg 100 mg/12 hours 160/800/12 hours |
dna 350 800 300 160-700 dna 521 25-85Ü 75 79 (5% active) 50-250 >/= 200 220 92 150/400 |
60 42 >90 97 40-50 >40 80 90 26-32 70-80 55 55/50 (0/37% active) |
| dna, Data not available. *Urinary levels based on single oral dose of drug unless otherwise indicated. ÜRefers to formaldehyde concentration in urine |
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