Table 6

Clinical Manifestations of Cushing's Syndrome

 

All1 %

Disease2 %

Adenoma/
Carcinoma3 %

Obesity

90

91

93

Hypertension

80

63

93

Diabetes

80

32

79

Centripetal obesity

80

--

--

Weakness

80

25

82

Muscle Atrophy

70

34

--

Hirsuitism

70

59

79

Menstrual abnormal/
  sexual dysfunction

70

46

75

Purple striae

70

46

36

Moon Facies

60

--

--

Osteoporosis

50

29

54

Early bruising

50

54

57

Acne/pigmentation

50

32

--

Mental changes

50

47

57

Edema

50

15

--

Headache

40

21

46

Poor healing

40

--

--

1Hunt and Tyrell, 1978
2Wilson, 1984
3Scott, 1973

(From: Scott HW Jr: Surgery of the Adrenal Glands, HW Scott (ed). J.P. Lippincott Co: Philadelphia, 1990).

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