Reliable coverage of antimicrobials used in the treatment of urinary tract infections of commonly encountered pathogens
|
Antimicrobial or antimicrobial class |
Gram positive pathogens |
Gram negative pathogens |
| Amoxicillin/ampicillin | streptococcus enterococci |
E. coli P. mirabilis |
| Amoxicillin/clavulanate Ampicillin/sulbactam |
streptococcus staphylococcus (not MRSA) enterococci |
E. coli, P. mirabilis, H. influenzae, Klebsiella spp. |
| Antistaphyloccal penicillins | streptococcus staphylococcus (not MRSA) |
none |
| Antipseudomonal penicillins | streptococcus enterococci |
most including P.aeruginosa |
| 1st generation cephalosporins | streptococcus staphylococcus (not MRSA) |
E. coli, P. mirabilis, Klebsiella spp. |
| 2nd generation cephalosporins (cefamandole, cefuroxime, cefaclor) |
streptococcus staphylococcus (not MRSA) |
E. coli, P. mirabilis, H. influenzae, Klebsiella spp. |
| 2nd generation cephalosporins (cefoxitin, cefotetan) |
streptococcus | E. coli, Proteus spp. (incl. indole+), H. influenzae, Klebsiella spp. |
3rd generation cephalosporins |
streptococcus | most ceftazidime, cefoperazone - P. aeruginosa |
Aztreonam |
none | most including P. aeruginosa |
Aminoglycosides |
staphylococcus (urine) | most including P. aeruginosa |
Fluoroquinolones |
none | most including P. aeruginosa |
| Nitrofurantoin | staphylococcus (not MRSA) enterococci |
many Enterobacteriaceae (not Providencia, Serratia, Acinetobacter), Klebsiella spp. |
| Trimethoprim/sulfamethoxazole | streptococcus staphylococcus |
most Enterobacteriaceae (not P. aeruginosa) |
Vancomycin |
all including MRSA | none |
(Courtesy of Cambell's Urology 7th edition, with the permission of W.B. Saunders)